Originating from the 1994 movie: PCU.
This term is most used as a comeback when someone says or does something you dislike. Can be used just like: "blow me" but adds that extra bit of urban flavor. This saying will often confuse and insult simultaneously.
Dude 1: Why did you order cheese on my burger?
Dude 2: I went and got it, didn't I?
Dude 1: So?!
Dude 2: So! You can "Blow me where the pampers is!"