A Acronym that stands for Down To Fuck. DTF was first heard on the reality show "Jersey Shore". It refers to nasty slutty whore's who are willing to go home with some random guy they just met (In most cases the girl is drunk but not always) and fuck. Afterward the girl will usually leave on her own but in most cases the guy will kick her out once he has been satisfied.
Guy #1: Hey that chick I was dancing with seems like she's DTF so I'll catch up with you later
Guy#2: Ok bro, get it in. Hit me up after you kick her out.