The act of becoming so undeniably inebriated on various forms of alcohol and drugs that you absolutely cannot comprehend what the hell is going on around you or in your life.
"All these people are coming over and I don't know whether I should let them park here or pick them up somewhere. What do you think?"
"Umm, what? I don't know what the fuck is going on...
Man I'm fuckin' getting retarded."