It was made popular in late 60s East Coast slang, and then later devolved into, "homes" (silent L) at which point it was incorrectly assumed to be short for, "homeboy".
"Homeboy" is typically expressed as a familiar, friendly term often in the third person.
Unlike homeboy, holmes can be used in a variety of ways to denote friendship, aggressiveness, or dubious curiousity.
"Nice score on that one holmes!"
They were for a long period of time feared, this due to several rumors about the cult exercising several gruesome acts. Such as; crucifying meat.
However, a few hundred years after their official existence, a couple of archeologists found traces of various things which clarified the cult as a friendly and rather humorous one.
They are now considered to be one of thé most humorous cults, to have ever existed.
Yet, someone still believe they crucify meat.
Peter: Fuck the football team ! I'm in the Holmé shizzeeeee !!