Brain, voiced by Maurice LaMarche, was the genius, coming up with inpossible schemes to take over the world.
Pinky, voiced by Rob Paulsen, was the comical side kick with his phrase, "NARF!"
The show itself was aired from 1995-1998, and ran for 65 episodes. PatB won an Emmy for animation in 1996.
Brain: Same thing we do every night Pinky: Try to take over the world!
Pinky and the Brain is a classic, anyone would agree.