To do somethin in the manner of, or get money like someone born in the 1980's, or an 80's baby.
i.e; hustle/illegal activity of any kind but especially "crack" transactions. Could also refer to murder.
When spoken, the words "Eighty" and "Way" are usually drawn out and over emphasized. i.e; "That Eeiiighty Way!"
Ex 2: "when I see em i'ma merc ol' boy That 80 Way!"