When your in-laws come to stay for a weekend but stay significantly longer.
John: Holy crap dude, you look like you are in misery. Is everything ok?
Jim: I am so in-lawed, my wife's parents came to stay for a weekend 3 weeks ago, and still haven't left. I may never have the crapper to myself again, let alone watch what I want to on my TV. Misery is right.