"mano y mano" is Spanish for hand AND hand. Used for comedic effect, to imply mental simplicity, in several films. (Other variants include "mono y mono", Spanish for monkey and monkey = malapropism el mejor)
("MANO A MANO" is Spanish for hand TO hand - combat...
This is the actual phrase that is so often mutilated)
"He dun call me ig'nint!"
"Reeallly, ignorant of what? Where would one start."
Is layman's terms, a fight, but not usually followed closely to it's meaning. Often times, swords, or other weapons, not involved with guns or firearms, are associated with the term.