When something is so retarded and stupid (ex. Dating an ugly girl) you refer to it as "Blowin' Up Megaton" from the Xbox360, PS3 and PC game Fallout 3 created by Bethesda. Usually only people who have played Fallout3 would recognize the use of this word. An explosion so epic, when seen at the Balcony of Tenpenny Tower at night time, you notice you've made a big mistake. But hey, YOU GOT 500 CAPS FREE! :")
Gamer 1: Dude, I was thinking about asking that Jenna chick out...
Gamer 2: Don't do it, you fucking idiot! You'll blow up Megaton!