Left hand placement for special commands/spells in an online game that is from a third person-ish view, where you control a hero/champion in a person to person battle within a contained map that has an element of base/tower defense and attack with NPC (non-player character) minions. All this happens in a real time, multi-player map/environment and is considered an adventure, real-time strategy & role playing game like LOL (League Of Legends) or DOTA (Defender Of The Ancients).
As a summoner, I'll use the mouse to control my champions movement and target and then QWER POWER...*press Q* mega damage powers! *press W* Suck it monkeys! *press E* Boo-ya! *press R* How do you like them apples?! *frustrated keyboard smash* Why did I die?